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    Advanced Cryo-EM Methodology: Technical Enhancements for Practitioners

    Advanced Cryo-EM Methodology: Technical Enhancements for Practitioners

    BY vivianMay 16, 2025
    Health

    Advanced electron microscopy (EM) techniques provide powerful tools for studying material properties at atomic to molecular resolutions. For optimal performance with beam-sensitive materials, current protocols recommend using 300 kV field emission guns with a total accumulated dose of 40-60 e-/Ų. However, traditional EM faces inherent limitations

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    Cryo-EM Single Particle Analysis (SPA): Unveiling the Structural Mysteries of Biomolecules

    Cryo-EM Single Particle Analysis (SPA): Unveiling the Structural Mysteries of Biomolecules

    BY vivianMay 16, 2025
    Health

    What is Cryo-EM Single Particle Analysis (SPA)? Cryo-Electron Microscopy (Cryo-EM) is a technique that uses an electron microscope to observe samples, with the key feature being its ability to image samples in their native state at cryogenic temperatures, thus avoiding structural alterations that might occur during traditional sample preparation. C

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