At least 2-4 weeks publicity is required to establish exhaustion. Another factor capable of induce exhaustion are inhibitory receptors including programmed cell loss of life protein 1 (PD1), CTLA-4, T cell membrane protein-three (TIM3), and lymphocyte activation gene three protein (LAG3). Soluble molecules corresponding to cytokines IL-10 or TGF-β
Thursday, February 20